| Irvine to Stannington | 198.29 mi (319.11 km) |
| Irvine to Stansted Mountfitchet | 324.70 mi (522.55 km) |
| Irvine to Stanwell | 335.03 mi (539.17 km) |
| Irvine to Stapleford | 230.70 mi (371.27 km) |
| Irvine to Staveley | 209.94 mi (337.87 km) |
| Irvine to Stepney | 340.87 mi (548.57 km) |
| Irvine to Stevenage | 314.80 mi (506.61 km) |
| Irvine to Stevenston | 4.14 mi (6.67 km) |
| Irvine to Stirling | 44.34 mi (71.35 km) |
| Irvine to Stockport | 183.02 mi (294.54 km) |
| Irvine to Stocksbridge | 192.51 mi (309.82 km) |
| Irvine to Stockton-on-Tees | 150.70 mi (242.52 km) |
| Irvine to Stoke Gifford | 296.43 mi (477.05 km) |
| Irvine to Stoke-on-Trent | 206.73 mi (332.70 km) |
| Irvine to Stone | 213.50 mi (343.59 km) |
