| Irthlingborough to Seymour (Tennessee) | 4,040.09 mi (6,501.90 km) |
| Irthlingborough to Shady Hills (Florida) | 4,361.97 mi (7,019.91 km) |
| Irthlingborough to Shafter (California) | 5,335.30 mi (8,586.33 km) |
| Irthlingborough to Shaker Heights (Ohio) | 3,689.06 mi (5,936.97 km) |
| Irthlingborough to Shakopee (Minnesota) | 3,979.99 mi (6,405.18 km) |
| Irthlingborough to Sharon (Pennsylvania) | 3,659.00 mi (5,888.59 km) |
| Irthlingborough to Sharonville (Ohio) | 3,902.19 mi (6,279.96 km) |
| Irthlingborough to Shasta Lake (California) | 5,128.28 mi (8,253.17 km) |
| Irthlingborough to Shawnee (Kansas) | 4,310.34 mi (6,936.83 km) |
| Irthlingborough to Shawnee (Oklahoma) | 4,577.11 mi (7,366.15 km) |
| Irthlingborough to Sheboygan (Wisconsin) | 3,820.15 mi (6,147.94 km) |
| Irthlingborough to Shelby (North Carolina) | 3,979.48 mi (6,404.36 km) |
| Irthlingborough to Shelbyville (Indiana) | 3,943.47 mi (6,346.41 km) |
| Irthlingborough to Shelbyville (Kentucky) | 3,985.52 mi (6,414.07 km) |
| Irthlingborough to Shelbyville (Tennessee) | 4,165.15 mi (6,703.17 km) |
