| Irthlingborough to Scottsboro (Alabama) | 4,191.37 mi (6,745.35 km) |
| Irthlingborough to Scottsdale (Arizona) | 5,198.99 mi (8,366.97 km) |
| Irthlingborough to Scranton (Pennsylvania) | 3,460.19 mi (5,568.63 km) |
| Irthlingborough to Seabrook (Maryland) | 3,616.60 mi (5,820.36 km) |
| Irthlingborough to Seabrook (Texas) | 4,803.80 mi (7,730.97 km) |
| Irthlingborough to Seaford (New York) | 3,405.41 mi (5,480.48 km) |
| Irthlingborough to Seagoville (Texas) | 4,701.52 mi (7,566.36 km) |
| Irthlingborough to Seal Beach (California) | 5,399.19 mi (8,689.16 km) |
| Irthlingborough to Searcy (Arkansas) | 4,384.14 mi (7,055.60 km) |
| Irthlingborough to Seaside (California) | 5,348.43 mi (8,607.46 km) |
| Irthlingborough to SeaTac (Washington) | 4,735.41 mi (7,620.91 km) |
| Irthlingborough to Seattle (Washington) | 4,725.96 mi (7,605.70 km) |
| Irthlingborough to Sebastian (Florida) | 4,308.08 mi (6,933.18 km) |
| Irthlingborough to Sebring (Florida) | 4,363.87 mi (7,022.98 km) |
| Irthlingborough to Secaucus (New Jersey) | 3,423.56 mi (5,509.69 km) |
