| Irthlingborough to Stannington | 83.46 mi (134.31 km) |
| Irthlingborough to Stansted Mountfitchet | 45.32 mi (72.93 km) |
| Irthlingborough to Stanwell | 60.21 mi (96.90 km) |
| Irthlingborough to Stapleford | 50.14 mi (80.68 km) |
| Irthlingborough to Staveley | 72.17 mi (116.14 km) |
| Irthlingborough to Stepney | 60.90 mi (98.00 km) |
| Irthlingborough to Stevenage | 34.02 mi (54.74 km) |
| Irthlingborough to Stevenston | 284.49 mi (457.84 km) |
| Irthlingborough to Stirling | 294.34 mi (473.70 km) |
| Irthlingborough to Stockport | 98.56 mi (158.61 km) |
| Irthlingborough to Stocksbridge | 89.47 mi (143.99 km) |
| Irthlingborough to Stockton-on-Tees | 157.88 mi (254.08 km) |
| Irthlingborough to Stoke Gifford | 99.50 mi (160.13 km) |
| Irthlingborough to Stoke-on-Trent | 80.66 mi (129.81 km) |
| Irthlingborough to Stone | 75.74 mi (121.89 km) |
