| Iowa City to University Place (Washington) | 1,566.38 mi (2,520.84 km) |
| Iowa City to Upland (California) | 1,509.92 mi (2,429.99 km) |
| Iowa City to Upper Arlington (Ohio) | 456.08 mi (734.00 km) |
| Iowa City to Upper Grand Lagoon (Florida) | 856.70 mi (1,378.73 km) |
| Iowa City to Upper Montclair (New Jersey) | 900.46 mi (1,449.15 km) |
| Iowa City to Urbana (Illinois) | 204.21 mi (328.65 km) |
| Iowa City to Urbana (Maryland) | 761.73 mi (1,225.89 km) |
| Iowa City to Urbana (Ohio) | 419.88 mi (675.74 km) |
| Iowa City to Urbandale (Iowa) | 116.22 mi (187.03 km) |
| Iowa City to Utica (New York) | 836.78 mi (1,346.66 km) |
| Iowa City to Uvalde (Texas) | 975.80 mi (1,570.40 km) |
| Iowa City to Vacaville (California) | 1,618.29 mi (2,604.38 km) |
| Iowa City to Vadnais Heights (Minnesota) | 247.46 mi (398.25 km) |
| Iowa City to Vail (Arizona) | 1,247.05 mi (2,006.93 km) |
| Iowa City to Valdosta (Georgia) | 875.80 mi (1,409.46 km) |
