| Iowa City to Seymour (Tennessee) | 577.69 mi (929.71 km) |
| Iowa City to Shady Hills (Florida) | 1,045.77 mi (1,683.00 km) |
| Iowa City to Shafter (California) | 1,547.03 mi (2,489.71 km) |
| Iowa City to Shaker Heights (Ohio) | 515.82 mi (830.14 km) |
| Iowa City to Shakopee (Minnesota) | 236.71 mi (380.95 km) |
| Iowa City to Sharon (Pennsylvania) | 571.64 mi (919.97 km) |
| Iowa City to Sharonville (Ohio) | 408.58 mi (657.55 km) |
| Iowa City to Shasta Lake (California) | 1,597.29 mi (2,570.58 km) |
| Iowa City to Shawnee (Kansas) | 251.09 mi (404.09 km) |
| Iowa City to Shawnee (Oklahoma) | 525.08 mi (845.03 km) |
| Iowa City to Sheboygan (Wisconsin) | 240.68 mi (387.34 km) |
| Iowa City to Shelby (North Carolina) | 695.72 mi (1,119.65 km) |
| Iowa City to Shelbyville (Indiana) | 335.32 mi (539.65 km) |
| Iowa City to Shelbyville (Kentucky) | 409.99 mi (659.82 km) |
| Iowa City to Shelbyville (Tennessee) | 505.97 mi (814.28 km) |
