| Iowa City to Security-Widefield (Colorado) | 723.30 mi (1,164.04 km) |
| Iowa City to Sedalia (Missouri) | 222.77 mi (358.52 km) |
| Iowa City to Sedro-Woolley (Washington) | 1,558.79 mi (2,508.62 km) |
| Iowa City to Seguin (Texas) | 908.05 mi (1,461.36 km) |
| Iowa City to Selden (New York) | 959.66 mi (1,544.42 km) |
| Iowa City to Selma (Alabama) | 684.59 mi (1,101.73 km) |
| Iowa City to Selma (California) | 1,538.64 mi (2,476.20 km) |
| Iowa City to Selma (Texas) | 916.03 mi (1,474.21 km) |
| Iowa City to Seminole (Florida) | 1,074.35 mi (1,729.00 km) |
| Iowa City to Seven Hills (Ohio) | 510.00 mi (820.76 km) |
| Iowa City to Seven Oaks (South Carolina) | 771.88 mi (1,242.22 km) |
| Iowa City to Severn (Maryland) | 798.71 mi (1,285.39 km) |
| Iowa City to Severna Park (Maryland) | 806.20 mi (1,297.45 km) |
| Iowa City to Sevierville (Tennessee) | 585.04 mi (941.53 km) |
| Iowa City to Seymour (Indiana) | 351.05 mi (564.95 km) |
