| Indianapolis to Storm Lake (Iowa) | 510.05 mi (820.85 km) |
| Indianapolis to Storrs (Connecticut) | 739.36 mi (1,189.88 km) |
| Indianapolis to Stoughton (Wisconsin) | 269.64 mi (433.95 km) |
| Indianapolis to Stow (Ohio) | 265.78 mi (427.73 km) |
| Indianapolis to Streamwood (Illinois) | 187.86 mi (302.34 km) |
| Indianapolis to Streator (Illinois) | 169.04 mi (272.05 km) |
| Indianapolis to Streetsboro (Ohio) | 271.61 mi (437.11 km) |
| Indianapolis to Strongsville (Ohio) | 250.11 mi (402.51 km) |
| Indianapolis to Stuart (Florida) | 932.83 mi (1,501.25 km) |
| Indianapolis to Stuarts Draft (Virginia) | 401.05 mi (645.43 km) |
| Indianapolis to Sturgis (Michigan) | 144.79 mi (233.02 km) |
| Indianapolis to Suamico (Wisconsin) | 349.77 mi (562.90 km) |
| Indianapolis to Sudley (Virginia) | 467.42 mi (752.24 km) |
| Indianapolis to Suffern (New York) | 637.36 mi (1,025.74 km) |
| Indianapolis to Suffolk (Virginia) | 557.74 mi (897.59 km) |
