| Indianapolis to St. Simons (Georgia) | 651.48 mi (1,048.45 km) |
| Indianapolis to Stafford (Texas) | 880.95 mi (1,417.75 km) |
| Indianapolis to Stallings (North Carolina) | 440.96 mi (709.65 km) |
| Indianapolis to Stamford (Connecticut) | 667.63 mi (1,074.44 km) |
| Indianapolis to Stanford (California) | 1,938.73 mi (3,120.08 km) |
| Indianapolis to Stanton (California) | 1,799.81 mi (2,896.51 km) |
| Indianapolis to Star (Idaho) | 1,578.70 mi (2,540.67 km) |
| Indianapolis to Starkville (Mississippi) | 461.03 mi (741.96 km) |
| Indianapolis to State College (Pennsylvania) | 442.30 mi (711.82 km) |
| Indianapolis to Staten Island (New York) | 635.21 mi (1,022.27 km) |
| Indianapolis to Statesboro (Georgia) | 562.56 mi (905.35 km) |
| Indianapolis to Statesville (North Carolina) | 398.70 mi (641.64 km) |
| Indianapolis to Staunton (Virginia) | 396.54 mi (638.16 km) |
| Indianapolis to Steamboat Springs (Colorado) | 1,091.01 mi (1,755.81 km) |
| Indianapolis to Steiner Ranch (Texas) | 928.11 mi (1,493.66 km) |
