| Indianapolis to Smyrna (Delaware) | 562.18 mi (904.74 km) |
| Indianapolis to Smyrna (Georgia) | 418.40 mi (673.34 km) |
| Indianapolis to Smyrna (Tennessee) | 263.95 mi (424.79 km) |
| Indianapolis to Snellville (Georgia) | 425.87 mi (685.37 km) |
| Indianapolis to Snoqualmie (Washington) | 1,844.80 mi (2,968.92 km) |
| Indianapolis to Snyder (Texas) | 954.80 mi (1,536.60 km) |
| Indianapolis to Socastee (South Carolina) | 576.88 mi (928.39 km) |
| Indianapolis to Socorro (Texas) | 1,256.89 mi (2,022.76 km) |
| Indianapolis to Soddy-Daisy (Tennessee) | 316.80 mi (509.85 km) |
| Indianapolis to Solana Beach (California) | 1,782.92 mi (2,869.33 km) |
| Indianapolis to Soledad (California) | 1,914.87 mi (3,081.69 km) |
| Indianapolis to Solon (Ohio) | 270.77 mi (435.76 km) |
| Indianapolis to Somers Point (New Jersey) | 615.18 mi (990.04 km) |
| Indianapolis to Somerset (Kentucky) | 203.81 mi (328.00 km) |
| Indianapolis to Somerset (New Jersey) | 616.67 mi (992.44 km) |
