| Indianapolis to Seymour (Tennessee) | 299.00 mi (481.20 km) |
| Indianapolis to Shady Hills (Florida) | 812.12 mi (1,306.98 km) |
| Indianapolis to Shafter (California) | 1,822.46 mi (2,932.97 km) |
| Indianapolis to Shaker Heights (Ohio) | 267.99 mi (431.29 km) |
| Indianapolis to Shakopee (Minnesota) | 509.22 mi (819.51 km) |
| Indianapolis to Sharon (Pennsylvania) | 313.15 mi (503.97 km) |
| Indianapolis to Sharonville (Ohio) | 98.76 mi (158.93 km) |
| Indianapolis to Shasta Lake (California) | 1,898.66 mi (3,055.60 km) |
| Indianapolis to Shawnee (Kansas) | 465.28 mi (748.79 km) |
| Indianapolis to Shawnee (Oklahoma) | 666.07 mi (1,071.93 km) |
| Indianapolis to Sheboygan (Wisconsin) | 285.75 mi (459.87 km) |
| Indianapolis to Shelby (North Carolina) | 399.42 mi (642.81 km) |
| Indianapolis to Shelbyville (Indiana) | 25.68 mi (41.33 km) |
| Indianapolis to Shelbyville (Kentucky) | 119.15 mi (191.75 km) |
| Indianapolis to Shelbyville (Tennessee) | 296.08 mi (476.50 km) |
