| Indianapolis to Security-Widefield (Colorado) | 994.07 mi (1,599.81 km) |
| Indianapolis to Sedalia (Missouri) | 386.34 mi (621.76 km) |
| Indianapolis to Sedro-Woolley (Washington) | 1,868.05 mi (3,006.34 km) |
| Indianapolis to Seguin (Texas) | 971.20 mi (1,562.99 km) |
| Indianapolis to Selden (New York) | 693.49 mi (1,116.06 km) |
| Indianapolis to Selma (Alabama) | 510.96 mi (822.31 km) |
| Indianapolis to Selma (California) | 1,820.67 mi (2,930.08 km) |
| Indianapolis to Selma (Texas) | 984.89 mi (1,585.03 km) |
| Indianapolis to Seminole (Florida) | 846.63 mi (1,362.52 km) |
| Indianapolis to Seven Hills (Ohio) | 259.47 mi (417.58 km) |
| Indianapolis to Seven Oaks (South Carolina) | 482.59 mi (776.66 km) |
| Indianapolis to Severn (Maryland) | 505.85 mi (814.09 km) |
| Indianapolis to Severna Park (Maryland) | 513.06 mi (825.70 km) |
| Indianapolis to Sevierville (Tennessee) | 303.32 mi (488.15 km) |
| Indianapolis to Seymour (Indiana) | 58.91 mi (94.80 km) |
