| Indianapolis to Sanford (Maine) | 832.62 mi (1,339.98 km) |
| Indianapolis to Sanford (North Carolina) | 482.69 mi (776.82 km) |
| Indianapolis to Sanger (California) | 1,815.06 mi (2,921.06 km) |
| Indianapolis to Santa Ana (California) | 1,795.58 mi (2,889.71 km) |
| Indianapolis to Santa Barbara (California) | 1,875.24 mi (3,017.91 km) |
| Indianapolis to Santa Clara (California) | 1,929.38 mi (3,105.03 km) |
| Indianapolis to Santa Clara (Oregon) | 1,907.90 mi (3,070.47 km) |
| Indianapolis to Santa Clarita (California) | 1,810.55 mi (2,913.79 km) |
| Indianapolis to Santa Cruz (California) | 1,940.47 mi (3,122.88 km) |
| Indianapolis to Santa Fe (New Mexico) | 1,118.18 mi (1,799.54 km) |
| Indianapolis to Santa Fe (Texas) | 879.05 mi (1,414.70 km) |
| Indianapolis to Santa Fe Springs (California) | 1,799.97 mi (2,896.78 km) |
| Indianapolis to Santa Maria (California) | 1,901.22 mi (3,059.72 km) |
| Indianapolis to Santa Monica (California) | 1,819.81 mi (2,928.70 km) |
| Indianapolis to Santa Paula (California) | 1,842.35 mi (2,964.98 km) |
