| Indianapolis to San Luis Obispo (California) | 1,905.29 mi (3,066.27 km) |
| Indianapolis to San Marcos (California) | 1,774.56 mi (2,855.88 km) |
| Indianapolis to San Marcos (Texas) | 955.06 mi (1,537.03 km) |
| Indianapolis to San Marino (California) | 1,797.73 mi (2,893.17 km) |
| Indianapolis to San Mateo (California) | 1,943.94 mi (3,128.47 km) |
| Indianapolis to San Pablo (California) | 1,937.95 mi (3,118.83 km) |
| Indianapolis to San Rafael (California) | 1,946.89 mi (3,133.21 km) |
| Indianapolis to San Ramon (California) | 1,920.24 mi (3,090.32 km) |
| Indianapolis to San Tan Valley (Arizona) | 1,477.96 mi (2,378.55 km) |
| Indianapolis to Sand Springs (Oklahoma) | 598.75 mi (963.60 km) |
| Indianapolis to Sandusky (Ohio) | 214.28 mi (344.86 km) |
| Indianapolis to Sandy (Oregon) | 1,861.73 mi (2,996.16 km) |
| Indianapolis to Sandy (Utah) | 1,353.33 mi (2,177.98 km) |
| Indianapolis to Sandy Springs (Georgia) | 415.28 mi (668.33 km) |
| Indianapolis to Sanford (Florida) | 808.14 mi (1,300.58 km) |
