| Imperial Beach to Scottsboro (Alabama) | 1,786.55 mi (2,875.17 km) |
| Imperial Beach to Scottsdale (Arizona) | 313.56 mi (504.63 km) |
| Imperial Beach to Scranton (Pennsylvania) | 2,343.84 mi (3,772.04 km) |
| Imperial Beach to Seabrook (Maryland) | 2,281.28 mi (3,671.37 km) |
| Imperial Beach to Seabrook (Texas) | 1,321.35 mi (2,126.50 km) |
| Imperial Beach to Seaford (New York) | 2,456.91 mi (3,954.01 km) |
| Imperial Beach to Seagoville (Texas) | 1,195.45 mi (1,923.90 km) |
| Imperial Beach to Seal Beach (California) | 98.71 mi (158.85 km) |
| Imperial Beach to Searcy (Arkansas) | 1,463.21 mi (2,354.80 km) |
| Imperial Beach to Seaside (California) | 387.11 mi (622.99 km) |
| Imperial Beach to SeaTac (Washington) | 1,063.08 mi (1,710.86 km) |
| Imperial Beach to Seattle (Washington) | 1,075.12 mi (1,730.24 km) |
| Imperial Beach to Sebastian (Florida) | 2,202.27 mi (3,544.21 km) |
| Imperial Beach to Sebring (Florida) | 2,152.24 mi (3,463.69 km) |
| Imperial Beach to Secaucus (New Jersey) | 2,426.76 mi (3,905.50 km) |
