| Imperial Beach to Enterprise (Nevada) | 261.00 mi (420.04 km) |
| Imperial Beach to Enumclaw (Washington) | 1,042.93 mi (1,678.43 km) |
| Imperial Beach to Ephrata (Pennsylvania) | 2,315.81 mi (3,726.93 km) |
| Imperial Beach to Erie (Colorado) | 846.45 mi (1,362.23 km) |
| Imperial Beach to Erie (Pennsylvania) | 2,120.20 mi (3,412.14 km) |
| Imperial Beach to Erlanger (Kentucky) | 1,866.10 mi (3,003.19 km) |
| Imperial Beach to Escanaba (Michigan) | 1,832.76 mi (2,949.54 km) |
| Imperial Beach to Escondido (California) | 39.16 mi (63.03 km) |
| Imperial Beach to Española (New Mexico) | 673.45 mi (1,083.81 km) |
| Imperial Beach to Essex (Maryland) | 2,302.47 mi (3,705.47 km) |
| Imperial Beach to Essex Junction (Vermont) | 2,482.92 mi (3,995.87 km) |
| Imperial Beach to Estelle (Louisiana) | 1,603.26 mi (2,580.20 km) |
| Imperial Beach to Estero (Florida) | 2,155.97 mi (3,469.70 km) |
| Imperial Beach to Euclid (Ohio) | 2,042.44 mi (3,286.99 km) |
| Imperial Beach to Eufaula (Alabama) | 1,861.69 mi (2,996.11 km) |
