| Humble to Enterprise (Nevada) | 1,226.39 mi (1,973.69 km) |
| Humble to Enumclaw (Washington) | 1,853.58 mi (2,983.04 km) |
| Humble to Ephrata (Pennsylvania) | 1,283.98 mi (2,066.37 km) |
| Humble to Erie (Colorado) | 886.42 mi (1,426.56 km) |
| Humble to Erie (Pennsylvania) | 1,188.91 mi (1,913.36 km) |
| Humble to Erlanger (Kentucky) | 869.40 mi (1,399.17 km) |
| Humble to Escanaba (Michigan) | 1,174.83 mi (1,890.71 km) |
| Humble to Escondido (California) | 1,299.58 mi (2,091.48 km) |
| Humble to Española (New Mexico) | 750.53 mi (1,207.87 km) |
| Humble to Essex (Maryland) | 1,244.48 mi (2,002.79 km) |
| Humble to Essex Junction (Vermont) | 1,568.26 mi (2,523.88 km) |
| Humble to Estelle (Louisiana) | 309.36 mi (497.86 km) |
| Humble to Estero (Florida) | 855.70 mi (1,377.12 km) |
| Humble to Euclid (Ohio) | 1,108.86 mi (1,784.54 km) |
| Humble to Eufaula (Alabama) | 613.58 mi (987.46 km) |
