| Humacao to Yonkers (New York) | 1,645.67 mi (2,648.44 km) |
| Humacao to Yorba Linda (California) | 3,365.49 mi (5,416.23 km) |
| Humacao to York (Pennsylvania) | 1,641.72 mi (2,642.09 km) |
| Humacao to Yorktown (Indiana) | 1,921.27 mi (3,091.98 km) |
| Humacao to Yorkville (Illinois) | 2,101.58 mi (3,382.16 km) |
| Humacao to Youngstown (Ohio) | 1,812.34 mi (2,916.68 km) |
| Humacao to Youngsville (Louisiana) | 1,838.96 mi (2,959.52 km) |
| Humacao to Ypsilanti (Michigan) | 1,965.85 mi (3,163.74 km) |
| Humacao to Yuba City (California) | 3,617.59 mi (5,821.95 km) |
| Humacao to Yucaipa (California) | 3,324.89 mi (5,350.89 km) |
| Humacao to Yucca Valley (California) | 3,290.18 mi (5,295.03 km) |
| Humacao to Yukon (Oklahoma) | 2,290.09 mi (3,685.55 km) |
| Humacao to Yulee (Florida) | 1,310.89 mi (2,109.67 km) |
| Humacao to Yuma (Arizona) | 3,171.47 mi (5,103.99 km) |
| Humacao to Zachary (Louisiana) | 1,807.29 mi (2,908.55 km) |
