| Humacao to St. Simons (Georgia) | 1,325.66 mi (2,133.44 km) |
| Humacao to Stafford (Texas) | 2,031.62 mi (3,269.58 km) |
| Humacao to Stallings (North Carolina) | 1,483.55 mi (2,387.55 km) |
| Humacao to Stamford (Connecticut) | 1,650.76 mi (2,656.64 km) |
| Humacao to Stanford (California) | 3,633.62 mi (5,847.74 km) |
| Humacao to Stanton (California) | 3,377.64 mi (5,435.79 km) |
| Humacao to Star (Idaho) | 3,414.00 mi (5,494.31 km) |
| Humacao to Starkville (Mississippi) | 1,772.32 mi (2,852.27 km) |
| Humacao to State College (Pennsylvania) | 1,719.59 mi (2,767.41 km) |
| Humacao to Staten Island (New York) | 1,627.02 mi (2,618.43 km) |
| Humacao to Statesboro (Georgia) | 1,399.21 mi (2,251.80 km) |
| Humacao to Statesville (North Carolina) | 1,526.45 mi (2,456.59 km) |
| Humacao to Staunton (Virginia) | 1,596.41 mi (2,569.17 km) |
| Humacao to Steamboat Springs (Colorado) | 2,874.80 mi (4,626.55 km) |
| Humacao to Steiner Ranch (Texas) | 2,179.69 mi (3,507.88 km) |
