| Humacao to St. George (Utah) | 3,162.55 mi (5,089.62 km) |
| Humacao to St. Helens (Oregon) | 3,749.35 mi (6,033.99 km) |
| Humacao to St. James (New York) | 1,629.23 mi (2,622.00 km) |
| Humacao to St. John (Indiana) | 2,055.02 mi (3,307.23 km) |
| Humacao to St. Joseph (Missouri) | 2,283.97 mi (3,675.69 km) |
| Humacao to St. Louis (Missouri) | 2,038.36 mi (3,280.42 km) |
| Humacao to St. Louis Park (Minnesota) | 2,437.31 mi (3,922.48 km) |
| Humacao to St. Marys (Georgia) | 1,316.23 mi (2,118.27 km) |
| Humacao to St. Marys (Pennsylvania) | 1,776.87 mi (2,859.60 km) |
| Humacao to St. Matthews (Kentucky) | 1,831.17 mi (2,946.99 km) |
| Humacao to St. Michael (Minnesota) | 2,460.78 mi (3,960.24 km) |
| Humacao to St. Paul (Minnesota) | 2,427.58 mi (3,906.82 km) |
| Humacao to St. Peter (Minnesota) | 2,432.70 mi (3,915.05 km) |
| Humacao to St. Peters (Missouri) | 2,060.00 mi (3,315.25 km) |
| Humacao to St. Petersburg (Florida) | 1,259.57 mi (2,027.09 km) |
