| Humacao to Silver Firs (Washington) | 3,747.24 mi (6,030.60 km) |
| Humacao to Silver Spring (Maryland) | 1,589.74 mi (2,558.44 km) |
| Humacao to Silver Springs Shores (Florida) | 1,272.06 mi (2,047.18 km) |
| Humacao to Silverdale (Washington) | 3,768.42 mi (6,064.68 km) |
| Humacao to Silverton (Oregon) | 3,736.71 mi (6,013.66 km) |
| Humacao to Simi Valley (California) | 3,423.51 mi (5,509.61 km) |
| Humacao to Simpsonville (South Carolina) | 1,527.01 mi (2,457.49 km) |
| Humacao to Sioux City (Iowa) | 2,455.59 mi (3,951.89 km) |
| Humacao to Sioux Falls (South Dakota) | 2,510.32 mi (4,039.97 km) |
| Humacao to Skokie (Illinois) | 2,093.91 mi (3,369.82 km) |
| Humacao to Sleepy Hollow (New York) | 1,655.34 mi (2,664.02 km) |
| Humacao to Slidell (Louisiana) | 1,721.50 mi (2,770.48 km) |
| Humacao to Smithfield (North Carolina) | 1,423.74 mi (2,291.28 km) |
| Humacao to Smithfield (Utah) | 3,151.29 mi (5,071.50 km) |
| Humacao to Smithville (Missouri) | 2,259.30 mi (3,635.99 km) |
