| Humacao to Saddlebrooke (Arizona) | 2,958.83 mi (4,761.77 km) |
| Humacao to Safety Harbor (Florida) | 1,268.35 mi (2,041.21 km) |
| Humacao to Saginaw (Michigan) | 2,040.65 mi (3,284.11 km) |
| Humacao to Saginaw (Texas) | 2,201.88 mi (3,543.58 km) |
| Humacao to Sahuarita (Arizona) | 2,958.12 mi (4,760.63 km) |
| Humacao to Saks (Alabama) | 1,638.87 mi (2,637.50 km) |
| Humacao to Salem (Massachusetts) | 1,709.41 mi (2,751.02 km) |
| Humacao to Salem (Ohio) | 1,807.03 mi (2,908.14 km) |
| Humacao to Salem (Oregon) | 3,747.45 mi (6,030.94 km) |
| Humacao to Salem (Virginia) | 1,578.64 mi (2,540.58 km) |
| Humacao to Salem Lakes (Wisconsin) | 2,132.54 mi (3,432.00 km) |
| Humacao to Salida (California) | 3,576.54 mi (5,755.88 km) |
| Humacao to Salina (Kansas) | 2,380.54 mi (3,831.11 km) |
| Humacao to Salinas (California) | 3,599.64 mi (5,793.05 km) |
| Humacao to Salisbury (Maryland) | 1,516.12 mi (2,439.96 km) |
