| Humacao to Reidsville (North Carolina) | 1,513.65 mi (2,435.98 km) |
| Humacao to Reisterstown (Maryland) | 1,612.26 mi (2,594.68 km) |
| Humacao to Rendon (Texas) | 2,188.11 mi (3,521.42 km) |
| Humacao to Reno (Nevada) | 3,526.65 mi (5,675.60 km) |
| Humacao to Renton (Washington) | 3,743.26 mi (6,024.20 km) |
| Humacao to Republic (Missouri) | 2,126.10 mi (3,421.63 km) |
| Humacao to Reston (Virginia) | 1,594.88 mi (2,566.71 km) |
| Humacao to Revere (Massachusetts) | 1,704.10 mi (2,742.49 km) |
| Humacao to Rexburg (Idaho) | 3,191.75 mi (5,136.63 km) |
| Humacao to Reynoldsburg (Ohio) | 1,815.13 mi (2,921.17 km) |
| Humacao to Rialto (California) | 3,345.18 mi (5,383.55 km) |
| Humacao to Richardson (Texas) | 2,168.65 mi (3,490.11 km) |
| Humacao to Richfield (Minnesota) | 2,431.01 mi (3,912.33 km) |
| Humacao to Richfield (Wisconsin) | 2,171.07 mi (3,494.00 km) |
| Humacao to Richland (Washington) | 3,590.97 mi (5,779.10 km) |
