| Humacao to Oswego (Illinois) | 2,098.65 mi (3,377.45 km) |
| Humacao to Oswego (New York) | 1,855.65 mi (2,986.38 km) |
| Humacao to Otsego (Minnesota) | 2,461.00 mi (3,960.60 km) |
| Humacao to Ottawa (Illinois) | 2,101.46 mi (3,381.98 km) |
| Humacao to Ottawa (Kansas) | 2,262.53 mi (3,641.19 km) |
| Humacao to Ottumwa (Iowa) | 2,229.72 mi (3,588.38 km) |
| Humacao to Overland (Missouri) | 2,046.21 mi (3,293.06 km) |
| Humacao to Overland Park (Kansas) | 2,246.03 mi (3,614.64 km) |
| Humacao to Overlea (Maryland) | 1,599.50 mi (2,574.14 km) |
| Humacao to Oviedo (Florida) | 1,212.96 mi (1,952.07 km) |
| Humacao to Owasso (Oklahoma) | 2,214.08 mi (3,563.22 km) |
| Humacao to Owatonna (Minnesota) | 2,394.12 mi (3,852.97 km) |
| Humacao to Owensboro (Kentucky) | 1,867.99 mi (3,006.24 km) |
| Humacao to Owings Mills (Maryland) | 1,609.03 mi (2,589.49 km) |
| Humacao to Owosso (Michigan) | 2,024.21 mi (3,257.65 km) |
