| Humacao to Odessa (Texas) | 2,460.67 mi (3,960.06 km) |
| Humacao to Ogden (Utah) | 3,146.34 mi (5,063.54 km) |
| Humacao to Oildale (California) | 3,446.84 mi (5,547.16 km) |
| Humacao to Ojus (Florida) | 1,063.71 mi (1,711.88 km) |
| Humacao to Okemos (Michigan) | 2,015.86 mi (3,244.22 km) |
| Humacao to Oklahoma City (Oklahoma) | 2,275.73 mi (3,662.43 km) |
| Humacao to Okmulgee (Oklahoma) | 2,202.64 mi (3,544.81 km) |
| Humacao to Olathe (Kansas) | 2,252.01 mi (3,624.26 km) |
| Humacao to Old Jamestown (Missouri) | 2,048.55 mi (3,296.83 km) |
| Humacao to Oldsmar (Florida) | 1,268.36 mi (2,041.22 km) |
| Humacao to Olean (New York) | 1,812.32 mi (2,916.65 km) |
| Humacao to Olive Branch (Mississippi) | 1,876.01 mi (3,019.14 km) |
| Humacao to Olivehurst (California) | 3,612.78 mi (5,814.20 km) |
| Humacao to Olney (Maryland) | 1,599.78 mi (2,574.60 km) |
| Humacao to Olympia (Washington) | 3,769.17 mi (6,065.89 km) |
