| Humacao to McKeesport (Pennsylvania) | 1,745.56 mi (2,809.21 km) |
| Humacao to McKinleyville (California) | 3,760.82 mi (6,052.46 km) |
| Humacao to McKinney (Texas) | 2,171.98 mi (3,495.46 km) |
| Humacao to McLean (Virginia) | 1,590.58 mi (2,559.79 km) |
| Humacao to McMinnville (Oregon) | 3,759.00 mi (6,049.53 km) |
| Humacao to McMinnville (Tennessee) | 1,719.23 mi (2,766.83 km) |
| Humacao to McNair (Virginia) | 1,596.68 mi (2,569.61 km) |
| Humacao to McPherson (Kansas) | 2,368.67 mi (3,812.01 km) |
| Humacao to Mead Valley (California) | 3,337.36 mi (5,370.96 km) |
| Humacao to Meadow Woods (Florida) | 1,210.29 mi (1,947.77 km) |
| Humacao to Meadowbrook (Virginia) | 1,507.44 mi (2,425.99 km) |
| Humacao to Meadville (Pennsylvania) | 1,830.31 mi (2,945.60 km) |
| Humacao to Mebane (North Carolina) | 1,486.29 mi (2,391.96 km) |
| Humacao to Mechanicsville (Virginia) | 1,515.77 mi (2,439.39 km) |
| Humacao to Medford (Massachusetts) | 1,705.52 mi (2,744.76 km) |
