| Humacao to Mauldin (South Carolina) | 1,531.47 mi (2,464.66 km) |
| Humacao to Maumee (Ohio) | 1,930.49 mi (3,106.82 km) |
| Humacao to Maumelle (Arkansas) | 1,997.26 mi (3,214.27 km) |
| Humacao to Mayagüez (Puerto Rico) | 86.67 mi (139.48 km) |
| Humacao to Mayfield Heights (Ohio) | 1,859.69 mi (2,992.88 km) |
| Humacao to Mays Chapel (Maryland) | 1,607.05 mi (2,586.29 km) |
| Humacao to Maywood (California) | 3,389.87 mi (5,455.47 km) |
| Humacao to Maywood (Illinois) | 2,090.03 mi (3,363.58 km) |
| Humacao to McAlester (Oklahoma) | 2,170.73 mi (3,493.45 km) |
| Humacao to McAllen (Texas) | 2,141.78 mi (3,446.86 km) |
| Humacao to McCalla (Alabama) | 1,678.55 mi (2,701.37 km) |
| Humacao to McComb (Mississippi) | 1,785.81 mi (2,873.98 km) |
| Humacao to McDonough (Georgia) | 1,549.41 mi (2,493.53 km) |
| Humacao to McFarland (California) | 3,460.35 mi (5,568.89 km) |
| Humacao to McHenry (Illinois) | 2,128.72 mi (3,425.84 km) |
