| Humacao to Indianola (Iowa) | 2,291.72 mi (3,688.17 km) |
| Humacao to Indio (California) | 3,276.65 mi (5,273.25 km) |
| Humacao to Inglewood (California) | 3,398.62 mi (5,469.56 km) |
| Humacao to Inkster (Michigan) | 1,959.10 mi (3,152.87 km) |
| Humacao to Inver Grove Heights (Minnesota) | 2,420.39 mi (3,895.24 km) |
| Humacao to Inwood (New York) | 1,622.47 mi (2,611.12 km) |
| Humacao to Iona (Florida) | 1,180.70 mi (1,900.16 km) |
| Humacao to Ionia (Michigan) | 2,051.42 mi (3,301.44 km) |
| Humacao to Iowa City (Iowa) | 2,220.68 mi (3,573.84 km) |
| Humacao to Irmo (South Carolina) | 1,453.59 mi (2,339.32 km) |
| Humacao to Irondale (Alabama) | 1,670.14 mi (2,687.83 km) |
| Humacao to Ironton (Ohio) | 1,735.25 mi (2,792.62 km) |
| Humacao to Irvine (California) | 3,364.33 mi (5,414.36 km) |
| Humacao to Irving (Texas) | 2,180.13 mi (3,508.59 km) |
| Humacao to Isabela (Puerto Rico) | 82.38 mi (132.58 km) |
