| Humacao to Sesena | 3,957.67 mi (6,369.25 km) |
| Humacao to Sestao | 4,008.93 mi (6,451.74 km) |
| Humacao to Sevilla | 3,823.60 mi (6,153.48 km) |
| Humacao to Sevilla La Nueva | 3,941.28 mi (6,342.88 km) |
| Humacao to Silla | 4,130.51 mi (6,647.41 km) |
| Humacao to Silleda | 3,741.74 mi (6,021.75 km) |
| Humacao to Sitges | 4,248.26 mi (6,836.92 km) |
| Humacao to Socuellamos | 4,003.02 mi (6,442.24 km) |
| Humacao to Soller | 4,296.06 mi (6,913.84 km) |
| Humacao to Solsona | 4,234.00 mi (6,813.96 km) |
| Humacao to Son Servera | 4,331.38 mi (6,970.68 km) |
| Humacao to Sonseca | 3,942.77 mi (6,345.28 km) |
| Humacao to Sopelana | 4,010.66 mi (6,454.53 km) |
| Humacao to Soria | 4,028.59 mi (6,483.39 km) |
| Humacao to Suances | 3,957.46 mi (6,368.92 km) |
