| Humacao to Entroncamento | 3,701.68 mi (5,957.28 km) |
| Humacao to Ericeira | 3,647.36 mi (5,869.85 km) |
| Humacao to Ermezinde | 3,711.64 mi (5,973.30 km) |
| Humacao to Esmoriz | 3,705.34 mi (5,963.17 km) |
| Humacao to Espinho | 3,705.15 mi (5,962.87 km) |
| Humacao to Esposende | 3,702.55 mi (5,958.68 km) |
| Humacao to Estarreja | 3,706.70 mi (5,965.35 km) |
| Humacao to Estoril | 3,646.47 mi (5,868.42 km) |
| Humacao to Estremoz | 3,744.74 mi (6,026.58 km) |
| Humacao to Evora | 3,726.02 mi (5,996.44 km) |
| Humacao to Fafe | 3,733.42 mi (6,008.37 km) |
| Humacao to Falagueira | 3,656.10 mi (5,883.92 km) |
| Humacao to Famalicao | 3,715.15 mi (5,978.95 km) |
| Humacao to Fanzeres | 3,712.05 mi (5,973.97 km) |
| Humacao to Faro | 3,715.73 mi (5,979.88 km) |
