| Humacao to Spello | 4,798.25 mi (7,722.04 km) |
| Humacao to Spilamberto | 4,706.31 mi (7,574.08 km) |
| Humacao to Spilimbergo | 4,787.78 mi (7,705.18 km) |
| Humacao to Spinea | 4,756.75 mi (7,655.25 km) |
| Humacao to Spoleto | 4,800.63 mi (7,725.86 km) |
| Humacao to Spoltore | 4,876.51 mi (7,847.98 km) |
| Humacao to Spresiano | 4,759.40 mi (7,659.52 km) |
| Humacao to Squinzano | 5,097.88 mi (8,204.25 km) |
| Humacao to Statte | 5,052.30 mi (8,130.90 km) |
| Humacao to Stezzano | 4,635.01 mi (7,459.32 km) |
| Humacao to Strada | 4,726.46 mi (7,606.51 km) |
| Humacao to Stradella | 4,619.92 mi (7,435.04 km) |
| Humacao to Striano | 4,913.34 mi (7,907.26 km) |
| Humacao to Subiaco | 4,828.03 mi (7,769.96 km) |
| Humacao to Sulmona | 4,869.19 mi (7,836.20 km) |
