| Hopkinsville to Seymour (Tennessee) | 216.84 mi (348.97 km) |
| Hopkinsville to Shady Hills (Florida) | 649.27 mi (1,044.90 km) |
| Hopkinsville to Shafter (California) | 1,764.08 mi (2,839.02 km) |
| Hopkinsville to Shaker Heights (Ohio) | 450.87 mi (725.61 km) |
| Hopkinsville to Shakopee (Minnesota) | 631.34 mi (1,016.05 km) |
| Hopkinsville to Sharon (Pennsylvania) | 481.88 mi (775.52 km) |
| Hopkinsville to Sharonville (Ohio) | 237.51 mi (382.23 km) |
| Hopkinsville to Shasta Lake (California) | 1,886.44 mi (3,035.93 km) |
| Hopkinsville to Shawnee (Kansas) | 426.73 mi (686.76 km) |
| Hopkinsville to Shawnee (Oklahoma) | 539.27 mi (867.87 km) |
| Hopkinsville to Sheboygan (Wisconsin) | 477.08 mi (767.79 km) |
| Hopkinsville to Shelby (North Carolina) | 348.09 mi (560.20 km) |
| Hopkinsville to Shelbyville (Indiana) | 207.91 mi (334.60 km) |
| Hopkinsville to Shelbyville (Kentucky) | 155.30 mi (249.93 km) |
| Hopkinsville to Shelbyville (Tennessee) | 108.80 mi (175.10 km) |
