| Hopkinsville to Scottsboro (Alabama) | 171.47 mi (275.95 km) |
| Hopkinsville to Scottsdale (Arizona) | 1,389.07 mi (2,235.50 km) |
| Hopkinsville to Scranton (Pennsylvania) | 706.60 mi (1,137.16 km) |
| Hopkinsville to Seabrook (Maryland) | 597.54 mi (961.65 km) |
| Hopkinsville to Seabrook (Texas) | 664.43 mi (1,069.29 km) |
| Hopkinsville to Seaford (New York) | 797.59 mi (1,283.59 km) |
| Hopkinsville to Seagoville (Texas) | 590.08 mi (949.64 km) |
| Hopkinsville to Seal Beach (California) | 1,730.93 mi (2,785.67 km) |
| Hopkinsville to Searcy (Arkansas) | 262.16 mi (421.91 km) |
| Hopkinsville to Seaside (California) | 1,891.38 mi (3,043.88 km) |
| Hopkinsville to SeaTac (Washington) | 1,908.76 mi (3,071.85 km) |
| Hopkinsville to Seattle (Washington) | 1,912.04 mi (3,077.14 km) |
| Hopkinsville to Sebastian (Florida) | 746.70 mi (1,201.70 km) |
| Hopkinsville to Sebring (Florida) | 736.13 mi (1,184.68 km) |
| Hopkinsville to Secaucus (New Jersey) | 770.76 mi (1,240.42 km) |
