| Hopkinsville to Olympia Heights (Florida) | 875.29 mi (1,408.65 km) |
| Hopkinsville to Omaha (Nebraska) | 552.01 mi (888.37 km) |
| Hopkinsville to On Top of the World Designated Place (Florida) | 612.89 mi (986.34 km) |
| Hopkinsville to Onalaska (Wisconsin) | 525.06 mi (845.00 km) |
| Hopkinsville to Oneida (New York) | 758.69 mi (1,220.99 km) |
| Hopkinsville to Oneonta (New York) | 764.74 mi (1,230.72 km) |
| Hopkinsville to Ontario (California) | 1,699.96 mi (2,735.83 km) |
| Hopkinsville to Ontario (Oregon) | 1,618.88 mi (2,605.34 km) |
| Hopkinsville to Opa-locka (Florida) | 866.89 mi (1,395.12 km) |
| Hopkinsville to Opelika (Alabama) | 312.24 mi (502.50 km) |
| Hopkinsville to Opelousas (Louisiana) | 510.05 mi (820.84 km) |
| Hopkinsville to Orange (California) | 1,716.21 mi (2,761.97 km) |
| Hopkinsville to Orange (Texas) | 588.23 mi (946.67 km) |
| Hopkinsville to Orange City (Florida) | 653.19 mi (1,051.20 km) |
| Hopkinsville to Orangeburg (South Carolina) | 438.96 mi (706.44 km) |
