| Homosassa Springs to St. Simons (Georgia) | 177.42 mi (285.53 km) |
| Homosassa Springs to Stafford (Texas) | 787.10 mi (1,266.72 km) |
| Homosassa Springs to Stallings (North Carolina) | 448.78 mi (722.23 km) |
| Homosassa Springs to Stamford (Connecticut) | 988.58 mi (1,590.97 km) |
| Homosassa Springs to Stanford (California) | 2,350.73 mi (3,783.13 km) |
| Homosassa Springs to Stanton (California) | 2,110.65 mi (3,396.77 km) |
| Homosassa Springs to Star (Idaho) | 2,132.26 mi (3,431.53 km) |
| Homosassa Springs to Starkville (Mississippi) | 491.30 mi (790.67 km) |
| Homosassa Springs to State College (Pennsylvania) | 868.89 mi (1,398.34 km) |
| Homosassa Springs to Staten Island (New York) | 941.57 mi (1,515.31 km) |
| Homosassa Springs to Statesboro (Georgia) | 254.59 mi (409.72 km) |
| Homosassa Springs to Statesville (North Carolina) | 491.46 mi (790.93 km) |
| Homosassa Springs to Staunton (Virginia) | 676.07 mi (1,088.03 km) |
| Homosassa Springs to Steamboat Springs (Colorado) | 1,590.55 mi (2,559.75 km) |
| Homosassa Springs to Steiner Ranch (Texas) | 928.18 mi (1,493.76 km) |
