| Homosassa Springs to St. George (Utah) | 1,878.27 mi (3,022.78 km) |
| Homosassa Springs to St. Helens (Oregon) | 2,471.25 mi (3,977.09 km) |
| Homosassa Springs to St. James (New York) | 987.61 mi (1,589.41 km) |
| Homosassa Springs to St. John (Indiana) | 915.68 mi (1,473.64 km) |
| Homosassa Springs to St. Joseph (Missouri) | 1,029.36 mi (1,656.60 km) |
| Homosassa Springs to St. Louis (Missouri) | 809.70 mi (1,303.09 km) |
| Homosassa Springs to St. Louis Park (Minnesota) | 1,262.66 mi (2,032.05 km) |
| Homosassa Springs to St. Marys (Georgia) | 146.35 mi (235.53 km) |
| Homosassa Springs to St. Marys (Pennsylvania) | 902.26 mi (1,452.05 km) |
| Homosassa Springs to St. Matthews (Kentucky) | 675.95 mi (1,087.84 km) |
| Homosassa Springs to St. Michael (Minnesota) | 1,285.91 mi (2,069.47 km) |
| Homosassa Springs to St. Paul (Minnesota) | 1,255.96 mi (2,021.28 km) |
| Homosassa Springs to St. Peter (Minnesota) | 1,242.80 mi (2,000.09 km) |
| Homosassa Springs to St. Peters (Missouri) | 829.30 mi (1,334.63 km) |
| Homosassa Springs to St. Petersburg (Florida) | 70.81 mi (113.95 km) |
