| Homosassa Springs to Somersworth (New Hampshire) | 1,188.81 mi (1,913.21 km) |
| Homosassa Springs to Somerton (Arizona) | 1,921.02 mi (3,091.59 km) |
| Homosassa Springs to Somerville (Massachusetts) | 1,134.79 mi (1,826.26 km) |
| Homosassa Springs to Somerville (New Jersey) | 927.94 mi (1,493.38 km) |
| Homosassa Springs to Sonoma (California) | 2,370.14 mi (3,814.37 km) |
| Homosassa Springs to Soquel (California) | 2,337.36 mi (3,761.62 km) |
| Homosassa Springs to South Bend (Indiana) | 913.20 mi (1,469.65 km) |
| Homosassa Springs to South Bradenton (Florida) | 93.36 mi (150.25 km) |
| Homosassa Springs to South Burlington (Vermont) | 1,196.49 mi (1,925.56 km) |
| Homosassa Springs to South Charleston (West Virginia) | 660.20 mi (1,062.49 km) |
| Homosassa Springs to South Daytona (Florida) | 95.86 mi (154.27 km) |
| Homosassa Springs to South El Monte (California) | 2,113.74 mi (3,401.74 km) |
| Homosassa Springs to South Elgin (Illinois) | 966.27 mi (1,555.05 km) |
| Homosassa Springs to South Euclid (Ohio) | 880.17 mi (1,416.50 km) |
| Homosassa Springs to South Farmingdale (New York) | 969.77 mi (1,560.69 km) |
