| Homosassa Springs to Smyrna (Delaware) | 825.10 mi (1,327.87 km) |
| Homosassa Springs to Smyrna (Georgia) | 367.99 mi (592.22 km) |
| Homosassa Springs to Smyrna (Tennessee) | 546.33 mi (879.23 km) |
| Homosassa Springs to Snellville (Georgia) | 359.07 mi (577.87 km) |
| Homosassa Springs to Snoqualmie (Washington) | 2,458.38 mi (3,956.38 km) |
| Homosassa Springs to Snyder (Texas) | 1,121.99 mi (1,805.67 km) |
| Homosassa Springs to Socastee (South Carolina) | 396.10 mi (637.47 km) |
| Homosassa Springs to Socorro (Texas) | 1,426.69 mi (2,296.03 km) |
| Homosassa Springs to Soddy-Daisy (Tennessee) | 471.24 mi (758.39 km) |
| Homosassa Springs to Solana Beach (California) | 2,069.05 mi (3,329.82 km) |
| Homosassa Springs to Soledad (California) | 2,302.44 mi (3,705.42 km) |
| Homosassa Springs to Solon (Ohio) | 871.02 mi (1,401.77 km) |
| Homosassa Springs to Somers Point (New Jersey) | 855.27 mi (1,376.42 km) |
| Homosassa Springs to Somerset (Kentucky) | 583.94 mi (939.77 km) |
| Homosassa Springs to Somerset (New Jersey) | 927.31 mi (1,492.36 km) |
