| Homosassa Springs to Silver Firs (Washington) | 2,479.02 mi (3,989.60 km) |
| Homosassa Springs to Silver Spring (Maryland) | 771.55 mi (1,241.68 km) |
| Homosassa Springs to Silver Springs Shores (Florida) | 37.90 mi (60.99 km) |
| Homosassa Springs to Silverdale (Washington) | 2,498.64 mi (4,021.17 km) |
| Homosassa Springs to Silverton (Oregon) | 2,455.58 mi (3,951.88 km) |
| Homosassa Springs to Simi Valley (California) | 2,153.80 mi (3,466.20 km) |
| Homosassa Springs to Simpsonville (South Carolina) | 409.15 mi (658.46 km) |
| Homosassa Springs to Sioux City (Iowa) | 1,220.76 mi (1,964.63 km) |
| Homosassa Springs to Sioux Falls (South Dakota) | 1,285.24 mi (2,068.40 km) |
| Homosassa Springs to Skokie (Illinois) | 958.96 mi (1,543.30 km) |
| Homosassa Springs to Sleepy Hollow (New York) | 979.06 mi (1,575.65 km) |
| Homosassa Springs to Slidell (Louisiana) | 447.09 mi (719.52 km) |
| Homosassa Springs to Smithfield (North Carolina) | 523.72 mi (842.85 km) |
| Homosassa Springs to Smithfield (Utah) | 1,867.03 mi (3,004.70 km) |
| Homosassa Springs to Smithville (Missouri) | 1,002.37 mi (1,613.16 km) |
