| Homosassa Springs to Salisbury (New York) | 967.99 mi (1,557.83 km) |
| Homosassa Springs to Salisbury (North Carolina) | 488.42 mi (786.04 km) |
| Homosassa Springs to Salmon Creek (Washington) | 2,461.59 mi (3,961.54 km) |
| Homosassa Springs to Salt Lake City (Utah) | 1,849.23 mi (2,976.04 km) |
| Homosassa Springs to Sammamish (Washington) | 2,468.79 mi (3,973.14 km) |
| Homosassa Springs to San Angelo (Texas) | 1,084.41 mi (1,745.19 km) |
| Homosassa Springs to San Anselmo (California) | 2,374.77 mi (3,821.82 km) |
| Homosassa Springs to San Antonio (Texas) | 964.96 mi (1,552.95 km) |
| Homosassa Springs to San Benito (Texas) | 943.61 mi (1,518.60 km) |
| Homosassa Springs to San Bernardino (California) | 2,070.63 mi (3,332.36 km) |
| Homosassa Springs to San Bruno (California) | 2,365.86 mi (3,807.49 km) |
| Homosassa Springs to San Buenaventura (California) | 2,181.34 mi (3,510.53 km) |
| Homosassa Springs to San Carlos (California) | 2,356.47 mi (3,792.37 km) |
| Homosassa Springs to San Carlos Park (Florida) | 167.27 mi (269.19 km) |
| Homosassa Springs to San Clemente (California) | 2,088.85 mi (3,361.68 km) |
