| Homosassa Springs to Oswego (Illinois) | 946.99 mi (1,524.03 km) |
| Homosassa Springs to Oswego (New York) | 1,065.39 mi (1,714.58 km) |
| Homosassa Springs to Otsego (Minnesota) | 1,287.84 mi (2,072.59 km) |
| Homosassa Springs to Ottawa (Illinois) | 936.05 mi (1,506.43 km) |
| Homosassa Springs to Ottawa (Kansas) | 994.25 mi (1,600.09 km) |
| Homosassa Springs to Ottumwa (Iowa) | 1,010.72 mi (1,626.59 km) |
| Homosassa Springs to Overland (Missouri) | 816.99 mi (1,314.82 km) |
| Homosassa Springs to Overland Park (Kansas) | 983.35 mi (1,582.55 km) |
| Homosassa Springs to Overlea (Maryland) | 805.90 mi (1,296.97 km) |
| Homosassa Springs to Oviedo (Florida) | 82.60 mi (132.93 km) |
| Homosassa Springs to Owasso (Oklahoma) | 929.20 mi (1,495.40 km) |
| Homosassa Springs to Owatonna (Minnesota) | 1,209.00 mi (1,945.70 km) |
| Homosassa Springs to Owensboro (Kentucky) | 672.02 mi (1,081.50 km) |
| Homosassa Springs to Owings Mills (Maryland) | 802.31 mi (1,291.20 km) |
| Homosassa Springs to Owosso (Michigan) | 984.21 mi (1,583.93 km) |
