| Homosassa Springs to Odessa (Texas) | 1,198.05 mi (1,928.07 km) |
| Homosassa Springs to Ogden (Utah) | 1,860.52 mi (2,994.21 km) |
| Homosassa Springs to Oildale (California) | 2,170.96 mi (3,493.82 km) |
| Homosassa Springs to Ojus (Florida) | 245.39 mi (394.91 km) |
| Homosassa Springs to Okemos (Michigan) | 965.63 mi (1,554.03 km) |
| Homosassa Springs to Oklahoma City (Oklahoma) | 987.85 mi (1,589.80 km) |
| Homosassa Springs to Okmulgee (Oklahoma) | 915.56 mi (1,473.46 km) |
| Homosassa Springs to Olathe (Kansas) | 988.56 mi (1,590.93 km) |
| Homosassa Springs to Old Jamestown (Missouri) | 822.43 mi (1,323.57 km) |
| Homosassa Springs to Oldsmar (Florida) | 53.20 mi (85.61 km) |
| Homosassa Springs to Olean (New York) | 945.24 mi (1,521.22 km) |
| Homosassa Springs to Olive Branch (Mississippi) | 603.21 mi (970.77 km) |
| Homosassa Springs to Olivehurst (California) | 2,326.14 mi (3,743.57 km) |
| Homosassa Springs to Olney (Maryland) | 779.33 mi (1,254.21 km) |
| Homosassa Springs to Olympia (Washington) | 2,496.11 mi (4,017.11 km) |
