| Homosassa Springs to Des Plaines (Illinois) | 961.63 mi (1,547.60 km) |
| Homosassa Springs to Desert Hot Springs (California) | 2,027.47 mi (3,262.90 km) |
| Homosassa Springs to DeSoto (Texas) | 889.41 mi (1,431.37 km) |
| Homosassa Springs to Destin (Florida) | 260.22 mi (418.79 km) |
| Homosassa Springs to Destrehan (Louisiana) | 477.85 mi (769.02 km) |
| Homosassa Springs to Detroit (Michigan) | 938.23 mi (1,509.93 km) |
| Homosassa Springs to Diamond Bar (California) | 2,100.44 mi (3,380.33 km) |
| Homosassa Springs to Diamond Springs (California) | 2,285.10 mi (3,677.51 km) |
| Homosassa Springs to Dickinson (North Dakota) | 1,657.68 mi (2,667.78 km) |
| Homosassa Springs to Dickinson (Texas) | 756.53 mi (1,217.52 km) |
| Homosassa Springs to Dickson (Tennessee) | 574.49 mi (924.56 km) |
| Homosassa Springs to Difficult Run (Virginia) | 757.75 mi (1,219.48 km) |
| Homosassa Springs to Dinuba (California) | 2,194.89 mi (3,532.34 km) |
| Homosassa Springs to Discovery Bay (California) | 2,321.64 mi (3,736.32 km) |
| Homosassa Springs to Dix Hills (New York) | 977.92 mi (1,573.81 km) |
