| Holyoke to Yonkers (New York) | 108.01 mi (173.82 km) |
| Holyoke to Yorba Linda (California) | 2,491.54 mi (4,009.75 km) |
| Holyoke to York (Pennsylvania) | 263.55 mi (424.14 km) |
| Holyoke to Yorktown (Indiana) | 682.98 mi (1,099.15 km) |
| Holyoke to Yorkville (Illinois) | 812.34 mi (1,307.34 km) |
| Holyoke to Youngstown (Ohio) | 420.18 mi (676.22 km) |
| Holyoke to Youngsville (Louisiana) | 1,360.73 mi (2,189.89 km) |
| Holyoke to Ypsilanti (Michigan) | 561.36 mi (903.41 km) |
| Holyoke to Yuba City (California) | 2,540.94 mi (4,089.25 km) |
| Holyoke to Yucaipa (California) | 2,449.77 mi (3,942.53 km) |
| Holyoke to Yucca Valley (California) | 2,415.21 mi (3,886.90 km) |
| Holyoke to Yukon (Oklahoma) | 1,422.21 mi (2,288.83 km) |
| Holyoke to Yulee (Florida) | 940.10 mi (1,512.95 km) |
| Holyoke to Yuma (Arizona) | 2,368.08 mi (3,811.06 km) |
| Holyoke to Zachary (Louisiana) | 1,297.65 mi (2,088.37 km) |
