| Holyoke to Worthington (Ohio) | 559.06 mi (899.71 km) |
| Holyoke to Wright (Florida) | 1,123.30 mi (1,807.78 km) |
| Holyoke to Wyandanch (New York) | 107.77 mi (173.43 km) |
| Holyoke to Wyandotte (Michigan) | 537.75 mi (865.42 km) |
| Holyoke to Wylie (Texas) | 1,445.53 mi (2,326.35 km) |
| Holyoke to Wyndham (Virginia) | 408.33 mi (657.15 km) |
| Holyoke to Wyoming (Michigan) | 666.00 mi (1,071.82 km) |
| Holyoke to Wyomissing (Pennsylvania) | 216.25 mi (348.02 km) |
| Holyoke to Xenia (Ohio) | 614.53 mi (988.99 km) |
| Holyoke to Yakima (Washington) | 2,347.45 mi (3,777.85 km) |
| Holyoke to Yankton (South Dakota) | 1,256.16 mi (2,021.59 km) |
| Holyoke to Yauco (Puerto Rico) | 1,704.82 mi (2,743.64 km) |
| Holyoke to Yazoo City (Mississippi) | 1,164.56 mi (1,874.18 km) |
| Holyoke to Yeadon (Pennsylvania) | 208.12 mi (334.93 km) |
| Holyoke to Yelm (Washington) | 2,439.54 mi (3,926.06 km) |
