| Holyoke to St. George (Utah) | 2,185.20 mi (3,516.75 km) |
| Holyoke to St. Helens (Oregon) | 2,463.76 mi (3,965.05 km) |
| Holyoke to St. James (New York) | 96.04 mi (154.57 km) |
| Holyoke to St. John (Indiana) | 764.33 mi (1,230.08 km) |
| Holyoke to St. Joseph (Missouri) | 1,165.78 mi (1,876.15 km) |
| Holyoke to St. Louis (Missouri) | 956.40 mi (1,539.18 km) |
| Holyoke to St. Louis Park (Minnesota) | 1,051.33 mi (1,691.95 km) |
| Holyoke to St. Marys (Georgia) | 932.91 mi (1,501.37 km) |
| Holyoke to St. Marys (Pennsylvania) | 307.76 mi (495.29 km) |
| Holyoke to St. Matthews (Kentucky) | 737.28 mi (1,186.53 km) |
| Holyoke to St. Michael (Minnesota) | 1,068.28 mi (1,719.23 km) |
| Holyoke to St. Paul (Minnesota) | 1,038.58 mi (1,671.43 km) |
| Holyoke to St. Peter (Minnesota) | 1,079.61 mi (1,737.46 km) |
| Holyoke to St. Peters (Missouri) | 971.17 mi (1,562.94 km) |
| Holyoke to St. Petersburg (Florida) | 1,144.53 mi (1,841.95 km) |
