| Holyoke to South Plainfield (New Jersey) | 145.80 mi (234.64 km) |
| Holyoke to South Portland (Maine) | 154.14 mi (248.06 km) |
| Holyoke to South Riding (Virginia) | 342.54 mi (551.26 km) |
| Holyoke to South River (New Jersey) | 151.75 mi (244.21 km) |
| Holyoke to South Salt Lake (Utah) | 2,017.41 mi (3,246.71 km) |
| Holyoke to South San Francisco (California) | 2,618.51 mi (4,214.08 km) |
| Holyoke to South San Jose Hills (California) | 2,494.49 mi (4,014.49 km) |
| Holyoke to South Sioux City (Nebraska) | 1,210.21 mi (1,947.65 km) |
| Holyoke to South St. Paul (Minnesota) | 1,035.28 mi (1,666.12 km) |
| Holyoke to South Valley (New Mexico) | 1,890.25 mi (3,042.06 km) |
| Holyoke to South Venice (Florida) | 1,184.27 mi (1,905.90 km) |
| Holyoke to South Whittier (California) | 2,503.43 mi (4,028.89 km) |
| Holyoke to South Yarmouth (Massachusetts) | 130.92 mi (210.70 km) |
| Holyoke to Southaven (Mississippi) | 1,059.51 mi (1,705.11 km) |
| Holyoke to Southchase (Florida) | 1,074.16 mi (1,728.70 km) |
