| Holyoke to Somersworth (New Hampshire) | 114.49 mi (184.26 km) |
| Holyoke to Somerton (Arizona) | 2,375.73 mi (3,823.36 km) |
| Holyoke to Somerville (Massachusetts) | 79.64 mi (128.17 km) |
| Holyoke to Somerville (New Jersey) | 152.61 mi (245.60 km) |
| Holyoke to Sonoma (California) | 2,603.63 mi (4,190.14 km) |
| Holyoke to Soquel (California) | 2,612.67 mi (4,204.68 km) |
| Holyoke to South Bend (Indiana) | 700.61 mi (1,127.53 km) |
| Holyoke to South Bradenton (Florida) | 1,162.78 mi (1,871.31 km) |
| Holyoke to South Burlington (Vermont) | 158.14 mi (254.50 km) |
| Holyoke to South Charleston (West Virginia) | 547.56 mi (881.22 km) |
| Holyoke to South Daytona (Florida) | 1,015.07 mi (1,633.59 km) |
| Holyoke to South El Monte (California) | 2,500.71 mi (4,024.50 km) |
| Holyoke to South Elgin (Illinois) | 802.45 mi (1,291.42 km) |
| Holyoke to South Euclid (Ohio) | 459.33 mi (739.22 km) |
| Holyoke to South Farmingdale (New York) | 111.41 mi (179.29 km) |
