| Holyoke to Shoreview (Minnesota) | 1,040.71 mi (1,674.86 km) |
| Holyoke to Shorewood (Illinois) | 801.66 mi (1,290.15 km) |
| Holyoke to Shorewood (Wisconsin) | 776.02 mi (1,248.88 km) |
| Holyoke to Short Hills (New Jersey) | 134.12 mi (215.85 km) |
| Holyoke to Short Pump (Virginia) | 410.63 mi (660.84 km) |
| Holyoke to Show Low (Arizona) | 2,084.22 mi (3,354.22 km) |
| Holyoke to Shreveport (Louisiana) | 1,337.66 mi (2,152.76 km) |
| Holyoke to Sicklerville (New Jersey) | 210.02 mi (337.99 km) |
| Holyoke to Sidney (Ohio) | 612.77 mi (986.15 km) |
| Holyoke to Sierra Madre (California) | 2,497.11 mi (4,018.71 km) |
| Holyoke to Sierra Vista (Arizona) | 2,187.38 mi (3,520.24 km) |
| Holyoke to Sierra Vista Southeast (Arizona) | 2,186.21 mi (3,518.37 km) |
| Holyoke to Signal Hill (California) | 2,514.52 mi (4,046.73 km) |
| Holyoke to Sikeston (Missouri) | 972.84 mi (1,565.63 km) |
| Holyoke to Siloam Springs (Arkansas) | 1,239.68 mi (1,995.07 km) |
