| Holyoke to San Diego (California) | 2,492.12 mi (4,010.67 km) |
| Holyoke to San Diego Country Estates (California) | 2,469.19 mi (3,973.78 km) |
| Holyoke to San Dimas (California) | 2,486.64 mi (4,001.86 km) |
| Holyoke to San Fernando (California) | 2,513.13 mi (4,044.50 km) |
| Holyoke to San Francisco (California) | 2,617.04 mi (4,211.71 km) |
| Holyoke to San Gabriel (California) | 2,501.88 mi (4,026.39 km) |
| Holyoke to San Germán (Puerto Rico) | 1,699.40 mi (2,734.92 km) |
| Holyoke to San Jacinto (California) | 2,454.53 mi (3,950.18 km) |
| Holyoke to San Jose (California) | 2,599.25 mi (4,183.09 km) |
| Holyoke to San Juan (Puerto Rico) | 1,690.21 mi (2,720.12 km) |
| Holyoke to San Juan (Texas) | 1,818.31 mi (2,926.29 km) |
| Holyoke to San Juan Capistrano (California) | 2,497.79 mi (4,019.81 km) |
| Holyoke to San Leandro (California) | 2,603.99 mi (4,190.71 km) |
| Holyoke to San Lorenzo (California) | 2,603.56 mi (4,190.02 km) |
| Holyoke to San Luis (Arizona) | 2,379.84 mi (3,829.98 km) |
